GWAS Summary Associations: Breast Cancer Risk (2020)

The results files provide summary association statistics for the analyses described in Zhang H et al (Nat Genet, 2020). There are three sets of results:

(a) overall breast cancer,
(b) subtype-specific breast cancer, and
(c) a meta-analysis of triple negative breast cancer and the BRCA1 breast cancer GWAS results from CIMBA.

The results files include results for the OncoArray and iCOGS datasets, and (for overall breast cancer) the combined results from additional GWAS. The summary results are based on imputation to the 1000 Genomes Project Phase 3 reference panel. The current results are for women of European ancestry only.


You are free to use make use of this resource in publications. If you do so, please cite: Zhang H et al (Nat Genet, 2020) and acknowledge the following:

The breast cancer genome-wide association analyses for BCAC and CIMBA were supported by Cancer Research UK (PPRPGM-Nov20\100002, C1287/A10118, C1287/A16563, C1287/A10710, C12292/A20861, C12292/A11174, C1281/A12014, C5047/A8384, C5047/A15007, C5047/A10692, C8197/A16565) and the Gray Foundation, The National Institutes of Health (CA128978, X01HG007492- the DRIVE consortium), the PERSPECTIVE project supported by the Government of Canada through Genome Canada and the Canadian Institutes of Health Research (grant GPH-129344) and the Ministère de l’Économie, Science et Innovation du Québec through Genome Québec and the PSRSIIRI-701 grant, the Quebec Breast Cancer Foundation, the European Community's Seventh Framework Programme under grant agreement n° 223175 (HEALTH-F2-2009-223175) (COGS), the European Union's Horizon 2020 Research and Innovation Programme (634935 and 633784), the Post-Cancer GWAS initiative (U19 CA148537, CA148065 and CA148112 - the GAME-ON initiative), the Department of Defence (W81XWH-10-1-0341), the Canadian Institutes of Health Research (CIHR) for the CIHR Team in Familial Risks of Breast Cancer (CRN-87521), the Komen Foundation for the Cure, the Breast Cancer Research Foundation and the Ovarian Cancer Research Fund. All studies and funders are listed in Zhang H et al (Nat Genet, 2020).

Terms of Use

The sample size and precision of the data presented should preclude identification of any individual subject. However, in downloading these data, you undertake not to attempt to identify individual subjects and not to repost these data to a third party website.

Description of field names in results file.

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